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Special Section on Menopause and Hormone Therapy for April 2025 Omar Al Yacoub Medical Countermeasures Special Section February 2024 JPET’s Top Reviewer Award ASPET 2024 Annual Meeting Pharmacology Awareness Week 1 2 3 4 5 Latest Fast Forward Articles You have access Rapid-onset, short-duration induction of colorectal contractions in anesthetized, adult, male rats. Jason B. Cook , Raymond Piatt , Edward Burgard , Karl B. Thor and Lesley Marson Journal of Pharmacology and Experimental Therapeutics May 6, 2024, JPET-AR-2023-001989; DOI: https://doi.org/10.1124/jpet.123.001989 You have access Protease-activated receptor 2: a promising therapeutic target for women’s cancers Himani Shah , David P Fairlie and Junxian Lim Journal of Pharmacology and Experimental Therapeutics May 6, 2024, JPET-MR-2024-002176; DOI: https://doi.org/10.1124/jpet.124.002176 You have access CAR and PPARα do not perform liquid-liquid phase separation in cells Pengfei Zhao , Shicheng Fan , Yanying Zhou , Min Huang , Yue Gao and Huichang Bi Journal of Pharmacology and Experimental Therapeutics May 6, 2024, JPET-AR-2024-002174; DOI: https://doi.org/10.1124/jpet.124.002174 You have access Targeting PFC dysfunction in pain Kai Kummer and Patrick L Sheets Journal of Pharmacology and Experimental Therapeutics May 3, 2024, JPET-MR-2023-002046; DOI: https://doi.org/10.1124/jpet.123.002046 You have access Central Nervous System Distributional Kinetics of Selected Histone Deacetylase Inhibitors Wenqiu Zhang , Ju-Hee Oh , Wenjuan Zhang , Courtney C. Aldrich , Rachael W Sirianni and William F. Elmquist Journal of Pharmacology and Experimental Therapeutics April 26, 2024, JPET-AR-2024-002170; DOI: https://doi.org/10.1124/jpet.124.002170 You have access Antinociceptive effects of α2/α3-subtype selective GABA A receptor positive allosteric modulators KRM-II-81 and NS16085 in rats: behavioral specificity Lakeisha A. Lewter , Kristen Woodhouse , V. V. N. Phani Babu Tiruveedhula , James M. Cook and Jun-Xu Li Journal of Pharmacology and Experimental Therapeutics April 26, 2024, JPET-AR-2023-002070; DOI: https://doi.org/10.1124/jpet.123.002070 View more published ahead of print articles About Journal of Pharmacology and Experimental Therapeutics A leading research journal in the field of pharmacology, JPET provides broad coverage of all aspects of the interactions of chemicals with biological systems, including autonomic, behavioral, cardiovascular, cellular, clinical, developmental, gastrointestinal, immuno-, neuro-, pulmonary, and renal pharmacology, as well as analgesics, drug abuse, metabolism and disposition, chemotherapy, and toxicology. Current issue Journal of Pharmacology and Experimental Therapeutics Vol. 389 , Issue S3 1 Jun 2024 Complete Issue (PDF) Table of Contents Table of Contents (PDF) Index by author Complete Issue (PDF) JPET is published continuously. Articles are added as they are ready and assigned to monthly issues. Check this site for new content or sign up for content alerts . TOP 10 REASONS TO SUBMIT TO JPET: Free ASPET member submission & reduced page charges. Free color figures. Free accepted paper PDF access. Opportunity to Highlight trainee authors. Showcase important & interesting articles each month. Timely proofs and listing in PubMed. Transfer option to any ASPET journal. A goal to initiate Podcasts for top accepted articles. A goal of 20 days submission to 1st decision - GOAL MET . A goal of 9 days from acceptance to publication. - GOAL MET. EDITOR’S CHOICE ARTICLES FOR MAY 2024: Paclitaxel Aggravating Radiation-Induced Pulmonary Fibrosis Is Associated with the Down-Regulation of the Negative Regulatory Function of Spry Beclin-1–Derived Peptide MP1 Attenuates Renal Fibrosis by Inhibiting the Wnt/β-Catenin Pathway A Promise to Keep, but Miles to Go Before We Sleep… Most Cited Most Read Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians. Functional Selectivity and Classical Concepts of Quantitative Pharmacology Abl Protein-Tyrosine Kinase Inhibitor STI571 Inhibits In Vitro Signal Transduction Mediated by c-Kit and Platelet-Derived Growth Factor Receptors The Prediction of Human Pharmacokinetic Parameters from Preclinical and In Vitro Metabolism Data Selective inhibition of receptor-coupled phospholipase C-dependent processes in human platelets and polymorphonuclear neutrophils. 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