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Britch PBPK Modeling to Assess Hepatic Pathways with a Single Probe Triiodothyronine Reduces Hypertensive Vascular Dysfunction GPR171 Regulates Opioid Signaling and Antinociception Impact of Repeated Intraperitoneal Methylcellulose 1 2 3 4 5 Latest Fast Forward Articles You have access Fentanyl but not Morphine Interacts with Non-Opioid Recombinant Human Neurotransmitter Receptors and Transporters Randy Torralva , Amy J Eshleman , Tracy L Swanson , Jennifer L Schmachtenberg , William E Schutzer , Shelley H Bloom , Katherine M Wolfrum , John F Reed and Aaron Janowsky Journal of Pharmacology and Experimental Therapeutics June 8, 2020, jpet.120.265561; DOI: https://doi.org/10.1124/jpet.120.265561 You have access Shaping microglia phenotypes through estrogen receptors: Relevance to sex-specific neuroinflammatory responses to brain injury and disease Maricedes Acosta-Martinez Journal of Pharmacology and Experimental Therapeutics June 8, 2020, jpet.119.264598; DOI: https://doi.org/10.1124/jpet.119.264598 You have access MK-8719, a novel and selective O-GlcNAcase inhibitor that reduces the formation of pathological tau and ameliorates neurodegeneration in a mouse model of tauopathy Xiaohai Wang , Wenping Li , Jacob Marcus , Michelle Pearson , Lixin Song , Karen Smith , Giuseppe Terracina , Julie Lee , Kwok-Lam Karen Hong , Sherry X. Lu , Lynn Hyde , Shu-Cheng Chen , David Kinsley , Jerry P. Melchor , Daniel J. Rubins , Xiangjun Meng , Eric Hostetler , Cyrille Sur , Lili Zhang , Joel B. Schachter , J. Fred Hess , Harold G. Selnick , David J. Vocadlo , Ernest J. McEachern , Jason M. Uslaner , Joseph L. Duffy and Sean M. Smith Journal of Pharmacology and Experimental Therapeutics June 3, 2020, jpet.120.266122; DOI: https://doi.org/10.1124/jpet.120.266122 You have access Nonclinical Characterization of the HIF-Prolyl Hydroxylase Inhibitor Roxadustat, a Novel Treatment for Anemia of Chronic Kidney Disease Ughetta del Balzo , Pierre E Signore , Gail Walkinshaw , Todd W Seeley , Mitchell C Brenner , Qingjian Wang , Guangjie Guo , Michael P Arend , Lee A Flippin , F. Aisha Chow , David C Gervasi , Christian H Kjaergaard , Ingrid Langsetmo , Volkmar Guenzler , David Y Liu , Steve J Klaus , Al Lin and Thomas B Neff Journal of Pharmacology and Experimental Therapeutics June 2, 2020, jpet.120.265181; DOI: https://doi.org/10.1124/jpet.120.265181 You have access Pharmacological Properties of Delta Opioid Receptor-Mediated Behaviors: Agonist Efficacy and Receptor Reserve Isaac J Dripps , Ruizhuo Chen , Amanda M Shafer , Kathryn E Livingston , Alexander Disney , Stephen M Husbands , John R Traynor , Kenner C Rice and Emily M Jutkiewicz Journal of Pharmacology and Experimental Therapeutics May 28, 2020, jpet.119.262717; DOI: https://doi.org/10.1124/jpet.119.262717 You have access [3H]Dopamine Uptake through the Dopamine and Norepinephrine Transporters is Decreased in the Prefrontal Cortex of Transgenic Mice Expressing HIV-1 Tat Protein Matthew Strauss , Bernadette O'Donovan , Yihzi Ma , Ziyu Xiao , Steven Lin , Michael T Bardo , Pavel I Ortinski , Jay P McLaughlin and Jun Zhu Journal of Pharmacology and Experimental Therapeutics May 27, 2020, jpet.120.266023; DOI: https://doi.org/10.1124/jpet.120.266023 View more published ahead of print articles About Journal of Pharmacology and Experimental Therapeutics A leading research journal in the field of pharmacology, JPET provides broad coverage of all aspects of the interactions of chemicals with biological systems, including autonomic, behavioral, cardiovascular, cellular, clinical, developmental, gastrointestinal, immuno-, neuro-, pulmonary, and renal pharmacology, as well as analgesics, drug abuse, metabolism and disposition, chemotherapy, and toxicology. Current issue Journal of Pharmacology and Experimental Therapeutics Vol. 374 , Issue 1 1 Jul 2020 Table of Contents About the Cover Index by author JPET is published continuously. Articles are added as they are ready and assigned to monthly issues. Check this site for new content or sign up for content alerts . EDITOR'S CHOICE ARTICLES FOR JUNE: Pharmacokinetic-Pharmacodynamic-Efficacy Modeling of ONO-7579, a Novel Pan–Tropomyosin Receptor Kinase Inhibitor, in a Murine Xenograft Tumor Model Investigation of Structure-Activity Relationships of Dexrazoxane Analogs Reveals Topoisomerase IIβ Interaction as a Prerequisite for Effective Protection against Anthracycline Cardiotoxicity Mechanistic PBPK Modeling of Urine pH Effect on Renal and Systemic Disposition of Methamphetamine and Amphetamine EDITOR'S CHOICE ARTICLES FOR JULY: The Development and Characterization of an scFv-Fc Fusion–Based Gene Therapy to Reduce the Psychostimulant Effects of Methamphetamine Abuse Most Read KBP-042 as Adjunct Therapy to Metformin Manifestations of METH Neurotoxicity PBPK Model of Hydroxychloroquine SEP-363856, a Novel, Non-D 2 Psychotropic Agent Nose-to-Brain Delivery More... 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